Tuesday, May 3, 2011

beta blockers, Cardiovascular Pharmacology Concepts

General Pharmacology

Beta-blockers are drugs that bind to beta-adrenoceptors and thereby block the binding of norepinephrine and epinephrine to these receptors. This inhibits normal sympathetic effects that act through these receptors. Therefore, beta-blockers are sympatholytic drugs. Some beta-blockers, when they bind to the beta-adrenoceptor, partially activate the receptor while preventing norepinephrine from binding to the receptor  blockers that represent Class I antiarrhythmics.

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